I think using a VM is a good choice. You get all the compatibility benefits while isolating it from your hardware.

There is one special program for some special hardware that I need for work, and I just run said program in a Windows VM. Even better, I can run the program without internet. So it’s completely safe!

Grayjay, available from F-droid and on desktop.

If you hate FUTO, you don’t have to give them money.